A lien is nothing more than a claim against your property. As soon as a tax is assessed against you, a statutory lien is created. In other words, a claim against your property in the amount of the tax owed. However, until a lien is filed with the County Courthouse (perfected), it is not enforceable against third parties.
The IRS typically files two liens, one on real property and one on personal property. This includes ALL your property. It is typically filed in your county of residence and in other counties the IRS knows or thinks you may have property. As a practical matter however, the IRS does not go after personal property unless you are completely uncooperative and the property has significant value. It is your home they are typically interested in.
There are only five circumstances under which the IRS will release a lien: